For two of these siblings, the vaccinated index patient was the most probable source of infection. While no symptomatic cases were reported among the household contacts (n=164) of vaccinated mumps patients (n=36), there were cases with serological evidence of asymptomatic infection among vaccinated household contacts (9 of 66 vaccinated siblings). We found that viral titers are higher for unvaccinated patients than for vaccinated patients during the 1st 3 days after onset of disease. We also investigated the occurrence of mumps infection among the household contacts of vaccinated mumps patients.
We compared mumps viral titers of oral fluid specimens obtained by quantitative PCR from vaccinated (n=60) and unvaccinated (n=111) mumps patients.
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